Endocrine Abstracts

Background: Multiple endocrine neoplasia type 1 (MEN1), is an autosomal dominant inherited disorder with high penentrance, characterized by the onset of multiple tumors, mainly in parathyroid, pituitary gland and gastroenteropancreatic tract. During the course of the disease pituitary adenomas (PA) occur in 20-65%, rarely as first clinical manifestation, and are often described as larger, more aggressive, and more resistant to conventional therapy than their sporadic counterpa...

Introduction: Neuroendocrine neoplasms (NEN) are heterogeneous tumors, usually sporadic and non-functioning, with a favorable long-term prognosis if localized. Metastases are common and survival outcomes of metastatic patients (pts) is worse than in localized disease.Aim: To investigate survival outcomes in a monocentric cohort of sporadic NEN.Materials and Methods: Clinical data of pts with histologically confirmed sporadic NEN, r...